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ADA, ADAF scientists' innovative research presented at AADR

April 26, 2016 Los Angeles — Researchers with the ADA Science Institute and the ADA Foundation Dr. Anthony Volpe Research Center showcased abstracts and other work March 16-19 during the American Association for Dental Research/Canadian Association for Dental Research Annual Meeting and Exhibition.

Below are summaries of their work. For more information on any of the research, email the ADA Science Institute, science@ada.org, or the ADA Foundation Dr. Anthony Volpe Research Center, vrc@ada.org.

ADA Science Institute researcher Daniel Halpin gave an oral presentation, "Effectiveness of Diverse Hearing Protection Devices in Dental Noise Exposure," presenting a review of hearing loss research in dentistry; and sharing insights and conclusions drawn from a laboratory evaluation of hearing protection devices available to dentists, including basic foam, complex passive filter and active level-dependent electroacoustic devices.

Henry Lukic gave a poster presentation, "Surface Finish Effect of Carbide Burs and Diamond Instruments on Four Classes of Composite Materials." ADA researchers asked the question, "Does a 30-fluted tungsten carbide bur finish your resin-based composite material better than an ultrafine diamond instrument?" This research examined how these two types of rotary instruments finished four broad classes of composites: heterogeneous microfilled (Heliomolar), micro-hybrid (Esthet-X HD), nanofilled (Filtek Supreme Ultra) and nano-hybrid (Kalore). Researchers found that the two types of rotary instruments finished the four classes of composite materials differently.

Cameron Estrich gave a poster presentation, "Cumulative Mercury Exposure and Peripheral Nerve Function in a Sample of U.S. Dentists." This research used ADA Health Screening data from 1997 to 2006 to calculate individual cumulative elemental mercury exposure and estimate its effect on peripheral nerve function. The researchers concluded that estimated cumulative mercury exposure suggests minimal, clinically irrelevant associations with decreased peripheral nerve function.

Spiro Megremis, Ph.D., director of research and laboratories at the ADA Science Institute, gave an oral presentation on "The Ability of Protective Filtering Devices and Shields to Block Transmission of 'Blue-Light' from Curing Units." In this study, researchers investigated the ability of a variety of commercially available protective filtering eye glasses and shields to block the transmission of blue-light coming from a broadband quartz tungsten halogen curing unit and a single-peak LED curing unit. Researchers found that four of 12 brands of protective filtering eye glasses and five of 10 brands of protective filtering shields allowed transmission of significant levels of blue-light from the curing units. It was calculated that the maximum permissible exposure duration allowed for an 8-hour workday could be exceeded at these transmission levels.

Dr. Jeffrey Kim, Ph.D., presented "Standardized Electronic-Cigarette Aerosol Alters Genomic Stability of Oral Epithelial Cells." Researchers standardized electronic cigarette testing parameters and identified potential hazardous byproducts in electronic cigarette aerosol that contribute to genomic instability in oral epithelial cells. The study concluded that chemical byproducts in electronic cigarette aerosol lead to genomic instability in oral epithelia, and chronic electronic cigarette exposure may increase mutagenic potential of oral epithelial cells.

Jirun Sun, Ph.D., presented "Design and Preparation of Self-healing Dental Composites," in which a new type of dental resin composites that can autonomously heal microcracks were successfully prepared.

Yin Yang, Ph.D., presented "Rapid Photo-polymerization of Vinylbenzylether Derivatives for Dental Applications." The objective of this project was to photo-polymerize vinylbenzyl ether monomers in clinically relevant conditions, which researchers said may have significant potential in designing and developing new dental materials.

Also, Dr. Thomas Hart, Ph.D., senior director at the Dr. Anthony Volpe Research Center, was the co-chair and speaker for one of the annual meeting's sessions, "Symposium on Genetic Testing for Diagnosis and Novel Therapies for Oral Diseases." This symposium offered an overview of the opportunities and challenges related to genetic testing in the field of dentistry and oral medicine.