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Evidence-Based Dentistry: Systematic Reviews
Search EBD content:
Periodontal Disease and Systemic Conditions
See also Pregnancy and Oral Health

The following systematic reviews are available for the topic periodontal disease and systemic conditions. Links to summaries of the systematic reviews are provided if available. These summaries are not developed by the ADA. In some cases, links are provided to the full-text copy of systematic reviews published in the Journal of the American Dental Association (JADA).

Associations between periodontal disease and risk for atherosclerosis, cardiovascular disease, and stroke. A systematic review.
Scannapieco FA, Bush RB, Paju S. Ann Periodontol 2003; 8(1): 38-53.

Associations between periodontal disease and risk for nosocomial bacterial pneumonia and chronic obstructive pulmonary disease. A systematic review.
Scannapieco FA, Bush RB, Paju S. Ann Periodontol 2003; 8(1): 54-69.

Does periodontal treatment improve glycemic control in diabetic patients? A meta-analysis of intervention studies.
Janket SJ, Wightman A, Baird AE, Van Dyke TE, Jones JA. J Dent Res 2005 Dec; 84(12):
1154-9.

Is periodontitis associated with an increased risk of coronary heart disease and preterm and/or low birth weight births?
Madianos PN, Bobetsis GA, Kinane DF. Journal of Clinical Periodontology 2002; 3: 22-36.

Meta-analysis of periodontal disease and risk of coronary heart disease and stroke.
Janket SJ, Baird AE, Chuang SK, Jones JA. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2003; 95(5): 559-69.

Periodontal disease and adverse pregnancy outcomes: a systematic review.
Xiong X, Buekens P, Fraser WD, Beck J, Offenbacher S. BJOG 2006; 113(2): 135-43.

Periodontal disease and adverse pregnancy outcomes: a systematic review.
Nugent JL, Barker PN. BJOG 2006 Jul;113(7):848.

Periodontal disease as a risk factor for adverse pregnancy outcomes. A systematic review.
Scannapieco FA, Bush RB, Paju S. Ann Periodontol 2003; 8(1): 70-8.

Periodontal diseases and the risk of coronary heart and cerebrovascular diseases: a meta-analysis.
Khader YS, Albashaireh ZS, Alomari MA. J Periodontol 2004; 75(8): 1046-53.

Periodontal diseases and the risk of preterm birth and low birth weight: a meta-analysis.
Khader YS, Ta'ani Q. J Periodontol 2005; 76(2): 161-5.

Periodontal status of diabetics compared with nondiabetics: a meta-analysis.
Khader YS, Dauod AS, El-Qaderi SS, Alkafajei A, Batayha WQ. J Diabetes Complications 2006; 20(1): 59-68.

Periodontal treatment and its effects on glycemic control: a review of the evidence.
Taylor GW. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 1999. 87(3): 311-6.

Periodontal infection and adverse pregnancy outcomes: a systematic review of epidemiological studies.
Vettore, M.V., et al., Cad Saude Publica, 2006. 22(10): p. 2041-53.

Systematic review of the association between respiratory diseases and oral health.
Azarpazhooh, A. and J.L. Leake, J Periodontol, 2006. 77(9): p. 1465-82.

Effect of periodontal treatment on serum C-reactive protein levels: a systematic review and meta-analysis.
Ioannidou, E., T. Malekzadeh, and A. Dongari-Bagtzoglou, J Periodontol, 2006. 77(10): p. 1635-42.

A systematic review of stress and psychological factors as possible risk factors for periodontal disease.
Peruzzo DC, Benatti BB, Ambrosano GM, Nogueira-Filho GR, Sallum EA, Casati MZ, Nociti FH Jr. J Periodontol 2007; 78(8): 1491-504.

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