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The following systematic reviews are available for the topic sealants. Links to summaries of the systematic reviews are provided if available. These summaries are not developed by the ADA. In some cases, links are provided to the full-text copy of systematic reviews published in the Journal of the American Dental Association (JADA).

Caries-inhibiting effect of preventive measures during orthodontic treatment with fixed appliances. A systematic review.
Derks A, Katsaros C, Frencken JE, van't Hof MA, Kuijpers-Jagtman AM. Caries Res 2004; 38(5): 413-20.

• Abstract

Caries-preventive effect of fissure sealants: a systematic review.
Mejare I, Lingstrom P, Petersson LG, Holm AK, Twetman S, Kallestal C, Nordenram G, Lagerlof F, Soder B, Norlund A, Axelsson S, Dahlgren H. Acta Odontol Scand 2003; 61(6):
321-30.

• Abstract
• DARE Summary
• NLH Summary

Effectiveness of methods used by dental professionals for the primary prevention of dental caries.
Rozier RG. J Dent Educ 2001; 65(10): 1063-72.

• Abstract

Factors influencing the effectiveness of sealants—a meta-analysis.
Llodra J, Bravo M, Delgado-Rodriguez M, Baca P, Galvez R. Community Dent Oral Epidemiol 1993;21: 261-8.

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Pit and fissure sealants for preventing dental decay in the permanent teeth of children and adolescents.
Ahovuo-Saloranta A, Hiiri A, Nordblad A, Worthington H, Makela M. Cochrane Database Syst Rev 2004;(3): CD001830.

• Abstract
• DARE Summary

Systematic review of conservative operative caries management strategies.
McComb D. J Dent Educ 2001; 65(10): 1154-61.

• Abstract

Retention of resin-based pit and fissure sealants: a systematic review.
Muller-Bolla, M., et al., Community Dent Oral Epidemiol, 2006. 34(5): p. 321-36.

• Abstract
• NLH Summary

Pit and fissure sealants versus fluoride varnishes for preventing dental decay in children and adolescents.
Hiiri, A., et al., Cochrane Database Syst Rev, 2006(4): p. CD003067.

• Abstract
• DARE Summary

Caries-preventive effect of resin-based and glass ionomer sealants over time: a systematic review.
N. Beiruti, J. E. Frencken, M. A. van 't Hof and W. H. van Palenstein Helderman. Community Dent Oral Epidemiol. 2006. 34(6): p. 403-9.

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Retention of resin-based pit and fissure sealants: a systematic review.
Muller-Bolla, M., et al.  Community Dent Oral Epidemiol, 2006. 34(5): 321-36.

• Abstract
• NLH Summary

Exploring four-handed delivery and retention of resin-based sealants.
Griffin SO, Jones K, Gray SK, Malvitz DM, Gooch BF. J Am Dent Assoc 2008;139(3):281-9; quiz 358.

• Abstract
• Full Text in JADA

The effectiveness of sealants in managing caries lesions.
Griffin SO, Oong E, Kohn W, Vidakovic B, Gooch BF, Bader J, et al. J Dent Res 2008;87(2):169-74.

• Abstract