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NIDCR devotes $24 million to tissue regeneration research

March 08, 2017

By Jennifer Garvin

Bethesda, Md. — The National Institute of Dental and Craniofacial Research announced March 7 that it has awarded $24 million to two resource centers dedicated to researching and developing new strategies for regenerating dental, oral and craniofacial tissues damaged by disease or injury.

The awards, totaling $24 million over three years, are part of the NIDCR's Dental, Oral, and Craniofacial Tissue Regeneration Consortium, also called DOCTRC. The consortium is designed to "shepherd new therapies through pre-clinical studies and into human clinical trials" and also help develop strategies and devices that could help repair or regenerate damaged tissues, including craniofacial bone, muscle and blood vessels, nerves, teeth and salivary glands, NIDCR said in a news release.

"By establishing this research consortium, NIDCR seeks to lead national efforts to accelerate the translation of promising DOC regenerative medicine therapies into the clinic," said Dr. Martha J. Somerman, NIDCR director. "DOCTRC is designed as a model for optimizing translation of scientific advances in this field."

The two research centers are:

  • The Center for Dental, Oral, and Craniofacial Tissue and Organ Regeneration and its principal investigators: Jeffrey C. Lotz, Ph.D., University of California, San Francisco; Yang Chai, D.D.S, Ph.D., University of Southern California; Yong Chen, Ph.D., University of Southern California; Kevin E. Healy, Ph.D., University of California, Berkeley; Ophir D. Klein, M.D., Ph.D., University of California, San Francisco; Nancy E. Lane, M.D., University of California, Davis; Michael Longaker, M.D., Stanford University, Mark M. Urata, D.D.S, M.D., University of Southern California; and Benjamin M. Wu, D.D.S., Ph.D., University of California, Los Angeles.
  • The Michigan-Pittsburgh-Wyss Resource Center: Supporting Regenerative Medicine in Dental, Oral and Craniofacial Technologies and its principal investigators: David H. Kohn, Ph.D., University of Michigan; William V. Giannobile, D.D.S., University of Michigan; David J. Mooney, Harvard University/Wyss Institute, Ph.D.; Charles Sfeir, D.D.S., Ph.D., University of Pittsburgh; and William R. Wagner, Ph.D., University of Pittsburgh.
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