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Nitrous oxide distribution ‘continues to improve’ after supply disruption

March 08, 2017

Silver Spring, Md. — Nitrous oxide bulk liquid is available and distribution to packaged gas locations continues to improve, the U.S. Food and Drug Administration said March 6, though the gas remains in shortage.

The FDA first issued a shortage notice Jan. 19 for nitrous oxide. Nitrous oxide was in the news in 2016 after an August explosion at a production facility in Florida that was operated by Nitrous Oxide Corp., an Airgas company.

But the FDA said March 6 “a return to full capacity throughout the Airgas supply chain is anticipated to return to normal by the end of March 2017.”

Access to nitrous oxide became a concern for some dentists as a result of the supply disruption, with several members calling the ADA and state dental associations with concerns earlier this year.

The ADA and the FDA encourage dental offices to report any shortages by emailing the agency at

Dentists can look for shortage notices, safety alerts and product recalls on the ADA Safety Alerts website by visiting

For more information on all drug shortages or supply issues, visit the FDA's website.