Clinical Practice Guidelines and Dental Evidence

Our collection of evidence-informed clinical practice guidelines that will help you improve your practice.
Antibiotic Stewardship Clinical Practice Statement (2026)

The ADA Council on Scientific Affairs reaffirms the importance of antibiotic stewardship in a new clinical practice statement.

Antibiotic Stewardship
New Light-based
Oral Cancer Guideline (2026 update)

These updated recommendations guide the use of cytology and vital staining adjuncts for early oral cancer detection in an interactive format.

Evidence-Based Clinical Practice Guidelines

The strongest resources to aid oral health professionals in clinical decision-making. Developed by a guideline panel, clinical and health guidelines critically appraise, summarize, and interpret relevant evidence to formulate recommendations that can be applied to patient care. Explore current clinical and health guidelines below.

Anesthesia & Sedation
Antibiotic Stewardship & Prophylaxis

Caries Management
Oral Cancer
Oral cancer (Living) 
Interactive recommendations on adjuncts for early detection of oral cancer.
Pain Management
Pain management (Living) 
Management of acute dental pain after tooth extraction or for temporary toothache relief.
Pain Periodontal Disease
Periodontitis treatment (2015)
Nonsurgical treatment of chronic periodontitis with scaling and root planing, with or without adjuncts.
Radiography & Radiation Safety

Patient selection x-ray recommendations (JADA 2026)
Patient selection criteria for 2-D and 3-D dental imaging featuring clinical scenarios.

Optimizing radiation safety (JADA 2024)
Appropriate dental X-ray use and updated radiation safety practices.

Education

Want to learn how to incorporate the latest scientific evidence into clinical practice? Check out these brief educational videos that demonstrate the techniques and principles of evidence-based dentistry.

Evidence-Based Dentistry

ADA Policy Statement on Evidence-Based Dentistry: The ADA defines the term evidence-based dentistry as an approach to oral health care that requires the judicious integration of systematic assessments of clinically relevant scientific evidence, relating to the patient’s oral and medical condition and history, with the dentist’s clinical expertise and the patient’s treatment needs and preferences.