Endodontic treatment entails the removal of the dental pulp and the subsequent shaping, cleaning, and filling or sealing of the root canals of a tooth. Endodontic materials must be highly biocompatible since they are sometimes placed directly on or against vital tissues. While mineral trioxide aggregates (MTAs) are commonly used, they suffer from poor handling properties, due to poor injectability, long setting times, and little washout resistance. Improper coronal sealing with some materials may lead to endodontic treatment failure. There is therefore a need for biocompatible endodontic materials with improved handling properties.